The equipoise arguemnt is fascinating here. If existing research already shows measurable bone density reduction and other documented harms, then claiming clinical uncertainty to justify an RCT becomes ethically questionable. The comparison to cancer treatment trials misses a key point cancr treatments address life-threatening conditions with clear diagnostic criteria, whereas this involves an unfalsifiable belief construct.
The equipoise arguemnt is fascinating here. If existing research already shows measurable bone density reduction and other documented harms, then claiming clinical uncertainty to justify an RCT becomes ethically questionable. The comparison to cancer treatment trials misses a key point cancr treatments address life-threatening conditions with clear diagnostic criteria, whereas this involves an unfalsifiable belief construct.